Question · asked by 1 review

Chloral hydrate/hydroxyzine vs A different sedative agent: Behaviour

Population
Children and adolescents (0 to 16 years) needing dental treatment
Intervention
Chloral hydrate/hydroxyzine
Comparison
A different sedative agent
Outcome
Behaviour

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 3 · 75%Very low 1 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Chloral hydrate/hydroxyzine vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes
Any behavioural score - Chloral hydrate/hydroxyzine versus (other sedatives): 235 (6); VERY LOW6 studies · 235 participantsVery low
Chloral hydrate/hydroxyzine vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2012) · Cochrane All outcomesearlier version CD003877.PUB4, superseded
Five studies (Avalos-Arenas 1998; Meyer 1990; Moody 1986; Reeves 1996; Torres-Perez 2007): no consistent significant behaviour differences vs comparators. Narrative.5 studiesGRADE not reported
Chloral hydrate/hydroxyzine vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded
Chloral hydrate/hydroxyzine head-to-head (Moody 1986; Meyer 1990; Poorman 1990; Tsinidou 1992; Reeves 1996; Avalos-Arena 1998): mostly no significant behaviour differences. Narrative.Not reportedGRADE not reported
Chloral hydrate/hydroxyzine vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded
Head-to-head chloral hydrate/hydroxyzine studies (Moody 1986; Meyer 1990 vs triazolam; Poorman 1990 +/-meperidine; Tsinidou 1992 vs temazepam; Reeves 1996 vs midazolam/acetaminophen; Avalos-Arena 1998 vs chloral…Not reportedGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Sedation of children undergoing dental treatment
2018 · Cochrane All outcomes
22 February 2018Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.