Sealing (resin sealant, glass ionomer cement, or polyurethane tape) vs Non-invasive / control treatment: Radiographic proximal caries lesion progression
- Population
- Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition)
- Intervention
- Sealing (resin sealant, glass ionomer cement, or polyurethane tape)
- Comparison
- Non-invasive / control treatment
- Outcome
- Radiographic proximal caries lesion progression
Sealing probably reduces the odds of proximal lesion progression compared with placebo (OR 0.27, 95% CI 0.18 to 0.42; moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Sealing (resin sealant, glass ionomer cement, or polyurethane tape) vs Non-invasive/control treatments (flossing, fluoride varnish/toothpaste, or dietary advice; placebo in one trial) Radiographic proximal caries lesion progression · Patients with non-cavitated proximal caries lesions · Longest available follow-up Sealing probably reduces the odds of proximal lesion progression compared with placebo (OR 0.27, 95% CI 0.18 to 0.42; moderate certainty). Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis. (2021) All outcomes | OR 0.27 [0.18, 0.42] | 7 studies · 320 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis. 2021 All outcomes | 6 April 2020 (from inception) | 22 | Critically Low / Critically Low |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Preventive and Therapeutic Proximal Sealing: A 3.5-Year Randomized Controlled Clinical Trial Follow-Up · 2017 · included by 1 of these review
- Sealing Distal Proximal Caries Lesions in First Primary Molars: Efficacy after 2.5 Years · 2010 · included by 1 of these review
- Effect of Glass-ionomer Cement on the Progression of Proximal Caries · 2010 · included by 1 of these review
- Efficacy of Sealing Proximal Early Active Lesions: An 18-Month Clinical Study Evaluated by Conventional and Subtraction Radiography · 2006 · included by 1 of these review
- A 2-year clinical evaluation of sealed noncavitated approximal posterior carious lesions in adolescents · 2005 · included by 1 of these review
- Alkilzy 2009 / Alkilzy 2011 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.