Question · asked by 1 review

Professionally-applied 12,300 ppm F APF foam, every 2 months vs 0 ppm F placebo foam: Number of participants with new demineralised lesions (DLs)

Population
Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Intervention
Professionally-applied 12,300 ppm F APF foam, every 2 months
Comparison
0 ppm F placebo foam
Outcome
Number of participants with new demineralised lesions (DLs)

Professionally-applied 12,300 ppm F APF foam, every 2 months may leads to lower number of participants with new demineralised lesions (DLs) compared with 0 ppm F placebo foam (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Professionally-applied 12,300 ppm F APF foam, every 2 months vs 0 ppm F placebo foam
Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; mean follow-up 18 months
Professionally-applied 12,300 ppm F APF foam, every 2 months may leads to lower number of participants with new demineralised lesions (DLs) compared with 0 ppm F placebo foam (low certainty).
Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane All outcomes
RR 0.26 [0.11, 0.57]1 study · 95 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment
2019 · Cochrane All outcomes
1 February 2019Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.