Question · asked by 1 review

Microinvasive techniques (resin infiltration or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care): Radiographic proximal caries lesion progression

Population
Children with non-cavitated proximal caries lesions in primary teeth (ages 3-9)
Intervention
Microinvasive techniques (resin infiltration or glass ionomer varnish)
Comparison
Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care)
Outcome
Radiographic proximal caries lesion progression

In primary teeth (5 trials), microinvasive techniques reduced radiographic proximal caries progression versus non-invasive measures (OR 0.38; ungraded subgroup).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Microinvasive techniques (resin infiltration or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care)
Radiographic progression of proximal caries lesions · Children with non-cavitated proximal caries lesions in primary teeth (ages 3-9) · Final follow-up (1 to 2 years across trials), Multiple countries (Brazil, Saudi Arabia, Netherlands, USA, Turkey, Switzerland, Germany, New Zealand, Chile, Thailand); dental clinic/community settings, Primary teeth (Fig. 6, subgroup 2.1.2)
In primary teeth (5 trials), microinvasive techniques reduced radiographic proximal caries progression versus non-invasive measures (OR 0.38; ungraded subgroup).
Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth-… (2025) All outcomes
OR 0.38 [0.25, 0.57]5 studies · 266 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and…
2025 All outcomes
May 202417Low / Critically Low
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.