Question · asked by 1 review
Preoperative ibuprofen vs placebo: Adverse events
- Population
- Children and adolescents having orthodontic separator placement (without local anaesthetic)
- Intervention
- Preoperative ibuprofen
- Comparison
- placebo
- Outcome
- Adverse events
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Preoperative ibuprofen vs Placebo Adverse events · Children and adolescents having orthodontic separator placement (without local anaesthetic) Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2016) · Cochrane All outcomes | One participant from the ibuprofen group and one from the placebo group reported a lip or cheek biting injury (Bernhardt 2001). No other adverse events were recorded for Bernhardt 2001 and Law 2000. | 2 studies | GRADE not reported |
Preoperative ibuprofen vs Placebo Adverse events · Children and adolescents having orthodontic separator placement (without local anaesthetic) Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2012) · Cochrane All outcomesearlier version CD008392.PUB2, superseded | One patient from the ibuprofen group and one from the placebo group reported a lip or cheek biting injury (Bernhardt 2001). No other adverse events were recorded for Bernhardt 2001 and Law 2000. | 2 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes | 2016-01 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.