NSAIDs vs COXIBs: Withdrawals due to adverse events
- Population
- acute gout
- Intervention
- NSAIDs
- Comparison
- COXIBs
- Outcome
- Withdrawals due to adverse events
NSAIDs probably leads to higher safety ‐ withdrawals due to adverse events Participant reported compared with COXIBs (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAIDs vs COXIBs Safety ‐ withdrawals due to adverse events Participant reported · people with acute gout NSAIDs probably leads to higher safety ‐ withdrawals due to adverse events Participant reported compared with COXIBs (moderate certainty). Non‐steroidal anti‐inflammatory drugs for acute gout (2014) · Cochrane Headline outcomes onlyearlier version CD010120.PUB2, superseded | RR 2.4 [1.35, 4.27] | 4 studies · 974 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Non‐steroidal anti‐inflammatory drugs for acute gout 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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- NSAIDs vs placebo · acute gout · 1 review
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.