Nitrous oxide vs carbon dioxide: Cardiopulmonary complications
It is very uncertain whether nitrous oxide changes cardiopulmonary complications compared with carbon dioxide (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Nitrous oxide vs carbon dioxide Cardiopulmonary complications · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia It is very uncertain whether nitrous oxide changes cardiopulmonary complications compared with carbon dioxide (very low certainty). Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery (2022) · Cochrane Headline outcomes only | Peto OR 2.62 [0.78, 8.85] | 3 studies · 204 participants | Very low |
Nitrous oxide vs carbon dioxide Cardiopulmonary complications · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia It is very uncertain whether nitrous oxide changes cardiopulmonary complications compared with carbon dioxide (very low certainty). Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery (2017) · Cochrane Headline outcomes onlyearlier version CD009569.PUB3, superseded | RR 2 [0.38, 10.43] | 2 studies · 140 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.