Question · asked by 1 review

Anti‐IgE mAb (omalizumab) vs usual care: Adverse events

Omalizumab showed no clear difference in adverse events compared with usual care (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Omalizumab vs usual care
Adverse events · autumn asthma exacerbations in children
Omalizumab showed no clear difference in adverse events compared with usual care (moderate certainty).
Interventions for autumn exacerbations of asthma in children (2018) · Cochrane Headline outcomes only
OR 0.99 [0.61, 1.58]1 study · 361 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for autumn exacerbations of asthma in children
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.