Question · asked by 1 review

Olanzapine vs NK1 antagonist: Serious adverse events

Population
cancer patients
Intervention
Olanzapine
Comparison
NK1 antagonist
Outcome
Serious adverse events

It is very uncertain whether olanzapine changes serious adverse events compared with NK1 antagonist (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Olanzapine vs NK1 antagonist
Serious adverse events · adults with cancer
It is very uncertain whether olanzapine changes serious adverse events compared with NK1 antagonist (very low certainty).
Olanzapine for the prevention and treatment of cancer‐related nausea and vomiting in adults (2018) · Cochrane Headline outcomes only
RR 0.33 [0.02, 7.32]Not reportedVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Olanzapine for the prevention and treatment of cancer‐related nausea and vomiting in adults
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.