Question · asked by 1 review

Hypoxia‐inducible factor (HIF) stabilisers vs placebo: Nonfatal myocardial infarction Median

It is very uncertain whether hypoxia‐inducible factor (HIF) stabilisers changes nonfatal myocardial infarction Median compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Hypoxia‐inducible factor (HIF) stabilisers vs placebo
Nonfatal myocardial infarction Median · people with CKD (including HD and PD)
It is very uncertain whether hypoxia‐inducible factor (HIF) stabilisers changes nonfatal myocardial infarction Median compared with placebo (very low certainty).
Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease (2022) · Cochrane Headline outcomes only
RR 1.29 [0.31, 5.36]3 studies · 822 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.