Question · asked by 1 review

Sucralfate vs placebo: Improvement in mucositis

Population
People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Intervention
Sucralfate
Comparison
placebo
Outcome
Improvement in mucositis

Sucralfate showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Sucralfate vs Placebo
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Sucralfate showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.
Interventions for treating oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomes
RR 0.93 [0.71, 1.24]1 study · 34 participantsGRADE not reported
Sucralfate vs Placebo
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Sucralfate showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.
Interventions for treating oral mucositis for patients with cancer receiving treatment (2007) · Cochrane All outcomesearlier version CD001973.PUB3, superseded
RR 0.93 [0.71, 1.24]1 study · 34 participantsGRADE not reported
Sucralfate vs Placebo
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Sucralfate showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.
Interventions for treating oral mucositis for patients with cancer receiving treatment (2004) · Cochrane All outcomesearlier version CD001973.PUB2, superseded
RR 0.93 [0.71, 1.24]1 study · 34 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral mucositis for patients with cancer receiving treatment
2010 · Cochrane All outcomes
2010-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.