Citrate vs unfractionated heparin: Successful prevention of clotting
Citrate showed no clear difference in successful prevention of clotting compared with unfractionated heparin (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Citrate vs unfractionated heparin Successful prevention of clotting · CRRT Citrate showed no clear difference in successful prevention of clotting compared with unfractionated heparin (moderate certainty). Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… (2020) · Cochrane Headline outcomes onlyearlier version CD012467.PUB2, superseded | RR 1.01 [0.77, 1.32] | 3 studies · 88 participants | Moderate |
Citrate vs unfractionated heparin Successful prevention of clotting · CRRT Citrate probably leads to higher successful prevention of clotting compared with unfractionated heparin (moderate certainty). Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… (2020) · Cochrane Headline outcomes only | RR 1.44 [1.1, 1.87] | 3 studies · 88 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.