Question · asked by 1 review

Tibolone vs placebo: Vasomotor symptoms (all doses)

Tibolone probably leads to lower vasomotor symptoms (all doses) compared with placebo (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Tibolone vs placebo
Vasomotor symptoms (all doses) · postmenopausal women with vasomotor symptoms
Tibolone probably leads to lower vasomotor symptoms (all doses) compared with placebo (moderate certainty).
Short‐term and long‐term effects of tibolone in postmenopausal women (2016) · Cochrane Headline outcomes only
OR 0.33 [0.27, 0.41]5 studies · 842 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Short‐term and long‐term effects of tibolone in postmenopausal women
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.