Question · asked by 1 review

Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct): Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)

Population
Adolescents/teenagers undergoing orthodontic treatment
Intervention
Experimental chewing adjuncts (bite wafers or chewing gum)
Comparison
No chewing gum, placebo, or control (no adjunct)
Outcome
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)

Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 4 · 80%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents undergoing orthodontic treatment · 6 hours
Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.
Non‐pharmacological interventions for alleviating pain during orthodontic treatment (2016) · Cochrane All outcomes
MD -1.39 [-3.24, 0.64]1 study · 39 participantsGRADE not reported
Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents undergoing orthodontic treatment · 3 days
Experimental chewing adjuncts (bite wafers or chewing gum) led to lower patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.
Non‐pharmacological interventions for alleviating pain during orthodontic treatment (2016) · Cochrane All outcomes
MD -29.16 [-51.67, -6.65]1 study · 39 participantsGRADE not reported
Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents undergoing orthodontic treatment · 7 days
Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.
Non‐pharmacological interventions for alleviating pain during orthodontic treatment (2016) · Cochrane All outcomes
MD -15.17 [-32.44, 2.11]2 studies · 96 participantsGRADE not reported
Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents undergoing orthodontic treatment · 24 hours
It is very uncertain whether experimental chewing adjuncts (bite wafers or chewing gum) changes patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct) (very low certainty).
Non‐pharmacological interventions for alleviating pain during orthodontic treatment (2016) · Cochrane All outcomes
MD -15.38 [-28.90, -1.86]2 studies · 96 participantsVery low
Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents undergoing orthodontic treatment · 1 day, Bite wafer subgroup (median data, opposite direction)
Non‐pharmacological interventions for alleviating pain during orthodontic treatment (2016) · Cochrane All outcomes
Otasevic 2006 (84 participants) presented median values only and reported higher median pain in the bite wafer group than the group who avoided chewing at one day (P = 0.006); data not suitable for meta‐analysis.1 study · 84 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Non‐pharmacological interventions for alleviating pain during orthodontic treatment
2016 · Cochrane All outcomes
2016-10Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.