Selenium (+LT4) vs placebo (+LT4): Change from baseline in assessment of symptoms such as mood, fatigue and muscle weakness Short‐Form Health Survey
Selenium (+LT4) may leads to higher change from baseline in assessment of symptoms such as mood, fatigue… compared with placebo (+LT4) (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Selenium (+LT4) vs placebo (+LT4) Change from baseline in assessment of symptoms such as mood, fatigue and muscle weakness Short‐Form Health Survey · participants with Hashimoto's thyroiditis. Selenium (+LT4) may leads to higher change from baseline in assessment of symptoms such as mood, fatigue… compared with placebo (+LT4) (low certainty). Selenium supplementation for Hashimoto's thyroiditis (2013) · Cochrane Headline outcomes only | RR 4.67 [1.61, 13.5] | 1 study · 36 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Selenium supplementation for Hashimoto's thyroiditis 2013 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.