Question · asked by 0 reviews

Lycopene plus intralesional betamethasone vs placebo: Severity of oral/mucosal burning pain/sensation

Population
Individuals in any age group with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis with trismus or restricted jaw movement
Intervention
Lycopene plus intralesional betamethasone
Comparison
placebo
Outcome
Severity of oral/mucosal burning pain/sensation

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Lycopene plus intralesional steroid (betamethasone) vs Placebo
Severity of oral/mucosal burning pain/sensation · Individuals in any age group with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous…
Interventions for managing oral submucous fibrosis (2008) · Cochrane All outcomesearlier version CD007156.PUB2, superseded
Kumar 2007: burning sensation reported but not based on a validated scale; data affected by attrition; not usable.1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing oral submucous fibrosis
2024 · Cochrane All outcomes
2022-09Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.