Question · asked by 1 review
Zinc chloride + sodium fluoride dentifrice vs Sodium fluoride (control) toothpaste: Adverse events
- Population
- Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological halitosis, non-oral halitosis, and severe chronic periodontitis (clinical attachment level 5 mm or more)
- Intervention
- Zinc chloride + sodium fluoride dentifrice
- Comparison
- Sodium fluoride (control) toothpaste
- Outcome
- Adverse events
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Zinc chloride + sodium fluoride dentifrice vs Control dentifrice (sodium fluoride) Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… Interventions for managing halitosis (2019) · Cochrane All outcomes | Payne 2011 reported 19 non-oral and 12 oral adverse effects. The oral effects were tingling sensation in lips, dry mouth or sore gums. | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for managing halitosis 2019 · Cochrane All outcomes | 2019-04 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.