Question · asked by 1 review

Fluoride varnish vs Fissure sealant (resin-based or glass ionomer): Caries incidence (proportion of enrolled children developing dentin caries, ICDAS 4-6)

Population
Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel caries (ICDAS 0-3)
Intervention
Fluoride varnish
Comparison
Fissure sealant (resin-based or glass ionomer)
Outcome
Caries incidence (proportion of enrolled children developing dentin caries, ICDAS 4-6)

Fluoride varnish and fissure sealant did not differ significantly in the proportion of children developing caries at 2 to 3 years (RR 1.12, 95% CI 0.60 to 2.09; 2 RCTs; ungraded).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Fluoride varnish applied biannually vs Fissure sealant (resin-based or glass ionomer)
Caries incidence (proportion of enrolled children developing dentin caries, ICDAS 4-6) · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures… · 2 to 3 years
Fluoride varnish and fissure sealant did not differ significantly in the proportion of children developing caries at 2 to 3 years (RR 1.12, 95% CI 0.60 to 2.09; 2 RCTs; ungraded).
Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a… (2020) All outcomes
RR 1.12 [0.60, 2.09]2 studies · 1072 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic Review and…
2020 All outcomes
February 20187Critically Low / Critically Low
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.