Question · asked by 1 review
Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline): Salivary osmolality (hydration level)
- Population
- Patients with drooling (sialorrhea) due to neurological disease
- Intervention
- Intraglandular botulinum neurotoxin (BoNT) injection
- Comparison
- No BoNT (placebo or pre-treatment baseline)
- Outcome
- Salivary osmolality (hydration level)
No included study reported salivary osmolality; this pre-planned outcome remains unassessed (no studies).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline) Salivary osmolality (hydration level) · Patients with drooling (sialorrhea) due to neurological disease · Neurological-disease populations with drooling (e.g., cerebral palsy, Parkinson disease, adults with sialorrhea); specialist clinical care No included study reported salivary osmolality; this pre-planned outcome remains unassessed (no studies). Oral health effects of botulinum toxin treatment for drooling: a systematic review. (2020) All outcomes | no estimate extracted | 0 studies | No studies found |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral health effects of botulinum toxin treatment for drooling: a systematic review. 2021 All outcomes | 2019-05 | 8 | Low / Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.