Question · asked by 1 review

Injectional collagenase vs placebo: Treatment‐related adverse effects

The review found no eligible studies for this question.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Injectional collagenase vs placebo
Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)
The review found no eligible studies for this question.
Non‐surgical therapies for Peyronie's disease (2023) · Cochrane Headline outcomes only
no estimate extractedNot reportedNo studies found
Injectional collagenase vs placebo
Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)
Injectional collagenase probably leads to higher treatment‐related adverse effects compared with placebo (moderate certainty).
Non‐surgical therapies for Peyronie's disease (2023) · Cochrane Headline outcomes only
RR 2.32 [1.98, 2.72]1 study · 832 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Non‐surgical therapies for Peyronie's disease
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.