Question · asked by 1 review

Summary of findings: ACT vs CQ: Effective treatment of the blood stage parasite As assessed by: Recurrent parasitaemia before day 28

Summary of findings: ACT showed no clear difference in effective treatment of the blood stage parasite As assessed by:… compared with CQ (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: ACT vs CQ
Effective treatment of the blood stage parasite As assessed by: Recurrent parasitaemia before day 28 · Adults and children with uncomplicated P. vivax malaria
Summary of findings: ACT showed no clear difference in effective treatment of the blood stage parasite As assessed by:… compared with CQ (high certainty).
Artemisinin‐based combination therapy for treating uncomplicated Plasmodium vivax malaria (2013) · Cochrane Headline outcomes only
RR 0.58 [0.18, 1.9]5 studies · 1622 participantsHigh
Summary of findings: ACT vs CQ
Effective treatment of the blood stage parasite As assessed by: Recurrent parasitaemia before day 28 · Adults and children with uncomplicated P. vivax malaria
Summary of findings: ACT showed no clear difference in effective treatment of the blood stage parasite As assessed by:… compared with CQ (high certainty).
Artemisinin‐based combination therapy for treating uncomplicated Plasmodium vivax malaria (2011) · Cochrane Headline outcomes onlyearlier version CD008492.PUB2, superseded
RR 1 [0.3, 3.39]4 studies · 1185 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Artemisinin‐based combination therapy for treating uncomplicated Plasmodium vivax malaria
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.