Sulodexide + local treatment vs local treatment: Ulcers completely healed
Sulodexide + local treatment may leads to higher proportion of ulcers completely healed (overall) compared with local treatment (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Sulodexide + local treatment vs local treatment Proportion of ulcers completely healed (overall) · patients with venous leg ulcers Sulodexide + local treatment may leads to higher proportion of ulcers completely healed (overall) compared with local treatment (low certainty). Sulodexide for treating venous leg ulcers (2016) · Cochrane Headline outcomes only | RR 1.66 [1.3, 2.12] | 3 studies · 438 participants | Low |
Sulodexide + local treatment vs local treatment Proportion of ulcers completely healed at 30 days · patients with venous leg ulcers It is very uncertain whether sulodexide + local treatment changes proportion of ulcers completely healed at 30 days compared with local treatment (very low certainty). Sulodexide for treating venous leg ulcers (2016) · Cochrane Headline outcomes only | RR 1.91 [1, 3.66] | 1 study · 114 participants | Very low |
Sulodexide + local treatment vs local treatment Proportion of ulcers completely healed at 60 days · patients with venous leg ulcers Sulodexide + local treatment may leads to higher proportion of ulcers completely healed at 60 days compared with local treatment (low certainty). Sulodexide for treating venous leg ulcers (2016) · Cochrane Headline outcomes only | RR 1.65 [1.2, 2.28] | 2 studies · 324 participants | Low |
Sulodexide + local treatment vs local treatment Proportion of ulcers completely healed at 90 days · patients with venous leg ulcers Sulodexide + local treatment may leads to higher proportion of ulcers completely healed at 90 days compared with local treatment (low certainty). Sulodexide for treating venous leg ulcers (2016) · Cochrane Headline outcomes only | RR 1.6 [1.17, 2.2] | 1 study · 230 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sulodexide for treating venous leg ulcers 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.