Question · asked by 1 review

Oral iron vs placebo or no treatment: Severe malaria

Oral iron leads to lower severe malaria Defined as clinical malaria with high‐grade… compared with placebo or no treatment (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Oral iron vs placebo or no treatment
Severe malaria Defined as clinical malaria with high‐grade parasitaemia or requiring admission · children in malaria‐endemic areas
Oral iron leads to lower severe malaria Defined as clinical malaria with high‐grade… compared with placebo or no treatment (high certainty).
Oral iron supplements for children in malaria‐endemic areas (2016) · Cochrane Headline outcomes only
RR 0.9 [0.81, 0.98]6 studies · 3421 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral iron supplements for children in malaria‐endemic areas
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.