Same question across reviews · CL0350
umbrella :: Silver diamine fluoride (SDF) -> Lesion arrest/remineralization
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
9
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | One systematic review found that SDF can be efficacious to decrease progression of root carious lesions (no numeric results reported) [24]. | NR | Ungraded |
38% silver diamine fluoride vs Placebo Coronal carious lesions arrest · Children with coronal carious lesions (permanent first molars) · Permanent first molars Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | Prevented Fraction 100 | 1 study | Ungraded |
38% silver diamine fluoride vs Fluoride varnish or placebo Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | Prevented Fraction 55–96 | 2 studies | Ungraded |
38% silver diamine fluoride vs Placebo or no treatment Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | RR 2.54 | 2 studies | Ungraded |
Silver diamine fluoride vs Not applicable (single-arm safety outcome) Adverse events: black staining of arrested lesions · Children and older adults treated with SDF for carious lesions Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | Eight systematic reviews reported adverse events; seven reported black staining of arrested carious lesions. Older adults rarely complained; discoloration was acceptable in children, concerning 7% of participants in… | NR | Ungraded |
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | Prevented Fraction 100–725 | 2 studies | Ungraded |
38% silver diamine fluoride vs Fluoride varnish or atraumatic restorative treatment Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | RR 1.66 | 2 studies | Ungraded |
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | One low risk of bias systematic review reported that 38% SDF was significantly more effective than placebo in arresting root carious lesions (pooled results were not calculated) [31]. | NR | Ungraded |
38% silver diamine fluoride vs Fluoride varnish, glass ionomer cement, or placebo Coronal carious lesions arrest (arrest rate) · Children with coronal carious lesions (primary dentition) · Primary dentition Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) | Arrest rate 65–91 | 6 studies | Ungraded |