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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

9 questions in 1 reviews · cluster CL0350

current versions
No studies 0 · 0%Ungraded 9 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
38% silver diamine fluoride vs Placebo
Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces)
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
One systematic review found that SDF can be efficacious to decrease progression of root carious lesions (no numeric results reported) [24].NRUngraded
38% silver diamine fluoride vs Placebo
Coronal carious lesions arrest · Children with coronal carious lesions (permanent first molars) · Permanent first molars
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
Prevented Fraction 1001 studyUngraded
38% silver diamine fluoride vs Fluoride varnish or placebo
Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
Prevented Fraction 55–962 studiesUngraded
38% silver diamine fluoride vs Placebo or no treatment
Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
RR 2.542 studiesUngraded
Silver diamine fluoride vs Not applicable (single-arm safety outcome)
Adverse events: black staining of arrested lesions · Children and older adults treated with SDF for carious lesions
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
Eight systematic reviews reported adverse events; seven reported black staining of arrested carious lesions. Older adults rarely complained; discoloration was acceptable in children, concerning 7% of participants in…NRUngraded
38% silver diamine fluoride vs Placebo
Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces)
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
Prevented Fraction 100–7252 studiesUngraded
38% silver diamine fluoride vs Fluoride varnish or atraumatic restorative treatment
Coronal carious lesions arrest · Children with coronal carious lesions (primary dentition) · Primary dentition
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
RR 1.662 studiesUngraded
38% silver diamine fluoride vs Placebo
Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces)
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
One low risk of bias systematic review reported that 38% SDF was significantly more effective than placebo in arresting root carious lesions (pooled results were not calculated) [31].NRUngraded
38% silver diamine fluoride vs Fluoride varnish, glass ionomer cement, or placebo
Coronal carious lesions arrest (arrest rate) · Children with coronal carious lesions (primary dentition) · Primary dentition
Silver diamine fluoride for managing carious lesions: an umbrella review. (2019)
Arrest rate 65–916 studiesUngraded