Same question across reviews · CL0297
intervention :: Xylitol/polyols -> Caries increment (DMFS/DMFT)
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
2
Questions
12
current versions
GRADE rated
8
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition defs index score (categories) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | Thorild 2003 defs score categories (very low-certainty): 1-3 defs RR 0.48 (95% CI 0.15 to 1.54); 3-4 defs RR 0.85 (95% CI 0.18 to 3.98); >=5 defs RR 0.28 (95% CI 0.01 to 6.78); 96 participants. | 1 study · 96 participants | Very low |
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition dmfs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | dmfs was listed in the SoF table but not assessed (not reported for this comparison). | 0 studies | No studies |
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition defs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | MD -0.28 [-0.83, 0.27] | 1 study · 96 participants | Very low |
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition dmft index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… · Children assessed at 5 yrs Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | MD -2.39 [-4.10, -0.68] | 1 study · 113 participants | Low |
Xylitol sucking tablets (1 g/day) vs No treatment Number of infants with a caries increment · Infants/young children (primary teeth; baseline about 1 to 3 years) · 18 months (24-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | RR 0.72 [0.35, 1.45] | 1 study · 118 participants | Ungraded |
Xylitol lozenges (5 g/day) vs Control lozenges (sucralose-sweetened placebo, no xylitol) Caries increment (DFS) · Adults · 33 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | PF 0.08 [-0.03, 0.20] | 1 study · 669 participants | Low |
Xylitol candy (7.5 g/day) vs Control (sorbitol) candy Caries increment (dmfs, primary and permanent teeth combined) · Children (mixed dentition; baseline about 8 years) · 36 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | One study (252 children) compared xylitol (7.5 g/day) candy with control (sorbitol) candy over 36 months. The data could not be used in analysis because the authors combined primary/deciduous and permanent teeth and… | 1 study · 252 participants | Ungraded |
Xylitol wipes (4.2 g/day) vs Control wipes (no xylitol) Number of infants with a caries increment (dmfs) · Infants (primary teeth) · 12 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | RR 0.14 [0.02, 1.07] | 1 study · 44 participants | Low |
Xylitol lozenges (4.7 g/day) vs No treatment Caries increment (DMFS) · Children (permanent teeth; baseline 8 to 10 years) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | PF -0.10 [-0.59, 0.39] | 1 study · 200 participants | Very low |
Xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy vs Control (sorbitol) tablets Number of infants with a caries increment (dmfs) · Infants (primary teeth; from about 1 month of age) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | RR 3.08 [0.69, 13.65] | 1 study · 62 participants | Very low |
Xylitol sucking tablets (1 g/day) vs No treatment Caries increment (dmfs) · Infants/young children (primary teeth; baseline about 1 to 3 years) · 18 months (24-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | PF 0.53 [0.001, 1.04] | 1 study · 118 participants | Very low |
Xylitol lozenges (4.7 g/day) vs No treatment Number of children with a caries increment · Children (permanent teeth; baseline 8 to 10 years) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | RR 1.02 [0.83, 1.26] | 1 study · 200 participants | Ungraded |