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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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12 questions in 2 reviews · cluster CL0297

current versions

No studies 1 · 8.3%Ungraded 3 · 25%Very low 5 · 41.7%Low 3 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition defs index score (categories) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane	Thorild 2003 defs score categories (very low-certainty): 1-3 defs RR 0.48 (95% CI 0.15 to 1.54); 3-4 defs RR 0.85 (95% CI 0.18 to 3.98); >=5 defs RR 0.28 (95% CI 0.01 to 6.78); 96 participants.	1 study · 96 participants	Very low
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition dmfs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane	dmfs was listed in the SoF table but not assessed (not reported for this comparison).	0 studies	No studies
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition defs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane	MD -0.28 [-0.83, 0.27]	1 study · 96 participants	Very low
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition dmft index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… · Children assessed at 5 yrs Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane	MD -2.39 [-4.10, -0.68]	1 study · 113 participants	Low
Xylitol sucking tablets (1 g/day) vs No treatment Number of infants with a caries increment · Infants/young children (primary teeth; baseline about 1 to 3 years) · 18 months (24-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	RR 0.72 [0.35, 1.45]	1 study · 118 participants	Ungraded
Xylitol lozenges (5 g/day) vs Control lozenges (sucralose-sweetened placebo, no xylitol) Caries increment (DFS) · Adults · 33 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	PF 0.08 [-0.03, 0.20]	1 study · 669 participants	Low
Xylitol candy (7.5 g/day) vs Control (sorbitol) candy Caries increment (dmfs, primary and permanent teeth combined) · Children (mixed dentition; baseline about 8 years) · 36 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	One study (252 children) compared xylitol (7.5 g/day) candy with control (sorbitol) candy over 36 months. The data could not be used in analysis because the authors combined primary/deciduous and permanent teeth and…	1 study · 252 participants	Ungraded
Xylitol wipes (4.2 g/day) vs Control wipes (no xylitol) Number of infants with a caries increment (dmfs) · Infants (primary teeth) · 12 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	RR 0.14 [0.02, 1.07]	1 study · 44 participants	Low
Xylitol lozenges (4.7 g/day) vs No treatment Caries increment (DMFS) · Children (permanent teeth; baseline 8 to 10 years) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	PF -0.10 [-0.59, 0.39]	1 study · 200 participants	Very low
Xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy vs Control (sorbitol) tablets Number of infants with a caries increment (dmfs) · Infants (primary teeth; from about 1 month of age) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	RR 3.08 [0.69, 13.65]	1 study · 62 participants	Very low
Xylitol sucking tablets (1 g/day) vs No treatment Caries increment (dmfs) · Infants/young children (primary teeth; baseline about 1 to 3 years) · 18 months (24-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	PF 0.53 [0.001, 1.04]	1 study · 118 participants	Very low
Xylitol lozenges (4.7 g/day) vs No treatment Number of children with a caries increment · Children (permanent teeth; baseline 8 to 10 years) · 24 months (48-month follow-up) Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane	RR 1.02 [0.83, 1.26]	1 study · 200 participants	Ungraded