Same question across reviews · CL0274
intervention :: Systemic/community fluoridation -> Adverse effects/fluorosis
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
3
current versions
GRADE rated
2
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Higher water fluoride concentration (fluoridated water; natural or artificial) vs Lower water fluoride concentration (concurrent control) Dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations · Cross-sectional Water fluoridation for the prevention of dental caries (2015) · Cochrane | OR 2.90 [2.05, 4.10] | 40 studies · 59630 participants | Low |
Higher water fluoride concentration (fluoridated water; natural or artificial) vs Lower water fluoride concentration (concurrent control) Dental fluorosis of any level (all severities) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations · Cross-sectional Water fluoridation for the prevention of dental caries (2015) · Cochrane | OR 3.60 [2.86, 4.53] | 90 studies · 180530 participants | Low |
Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water Adverse effects · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience) Water fluoridation for the prevention of dental caries (2015) · Cochrane | No evidence to determine whether cessation of a water fluoridation programme is associated with any harms. | 0 studies | No studies |