intervention :: Silver diamine fluoride (SDF) -> Lesion arrest/remineralization

Treatment success (caries lesion arrest or restoration survival) · Children (aged 3-11 y) with cavitated caries lesions in primary teeth · 6 months, 6-month follow-up

Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 3 weeks to 12 months, Overall (all comparators pooled)

Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 3 weeks to 12 months, SDF vs ART(GIC)

Caries arrestment at the surface level · Children and adults without systemic diseases affecting dental health · 12 months to 18 months

Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 6 to 12 months, SDF vs NAF

Caries arrest · Children and adults (with or without carious lesions) · 12 to 30 months, Primary dentition

Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 12 to 18 months, SDF vs NAF

Caries arrest · Children and adults (with or without carious lesions)

Caries arrest · Children and adults (with or without carious lesions) · Primary and permanent dentition

Caries arrest · Children and adults (with or without carious lesions) · 36 months, Permanent dentition (coronal)

Caries arrest · Children and adults (with or without carious lesions) · 24 months, Mixed dentition (coronal)

Caries arrest · Children and adults (with or without carious lesions) · 24 months, Permanent dentition (root)

Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 12 to 18 months, SDF vs NSF

Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 3 weeks to 12 months, SDF vs NSF

Caries arrest · Children and adults (with or without carious lesions) · 24 to 36 months, Primary dentition

Caries arrest · Children and adults (with or without carious lesions) · 12 months, Primary dentition (coronal)

Caries arrestment at the individual level · Children and adults without systemic diseases affecting dental health · 3 weeks to 12 months

Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 6 to 12 months, Overall (all comparators pooled)

Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 3 weeks to 12 months, SDF vs placebo

Caries arrest · Children and adults (with or without carious lesions) · 6 months, Primary dentition (coronal)

Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 12 to 18 months, Overall (all comparators pooled)

Caries arrest · Children and adults (with or without carious lesions) · Permanent dentition (root)

Caries arrestment at the tooth level · Children and adults without systemic diseases affecting dental health · 6 months to 12 months

Caries arrest · Children and adults (with or without carious lesions) · Permanent dentition (coronal)

Caries arrest · Children and adults (with or without carious lesions) · 18 months, Primary dentition (coronal)

Caries arrest · Children and adults (with or without carious lesions) · Permanent dentition

Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 6 to 12 months, SDF vs NSF

Caries arrest · Children and adults (with or without carious lesions) · 30 months, Primary dentition

Caries arrest · Children and adults (with or without carious lesions) · 24 months, Primary dentition

Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 6 to 12 months, SDF vs ART(GIC)

caries arrest · Patients with early enamel carious lesions on permanent molars (n=45) · 24 months

Remineralization/arrest of early enamel carious lesions · Patients with early enamel carious lesions on permanent molars · 24 months, Hamdi 2022 (early enamel lesions, Egypt)

Remineralization/arrest of early enamel carious lesions · Patients with early enamel carious lesions on permanent molars · 24 months, Hamdi 2022

Inactive (arrested) carious lesions on permanent first molars · Children with dental caries in permanent (first) molars · 36 months, Llodra 2005

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Follow-up up to 12 months (biannual application), SDF application frequency: biannual (every 6 months)

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · 24-30 months, SDF application frequency: variable (Fung 2018; 38% vs 12% SDF)

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Pooled across follow-up evaluations (1-36 months)

Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth · 18-30 months, 38% SDF vs 5% NaF varnish/water (Trieu et al. 2019 meta-analysis)

Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth · 6-48 months, Pooled caries-arrest proportion (Gao et al. 2016 meta-analysis)

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Pooled across 3-12 month follow-ups, Comparator: SDF vs ART (moderator analysis by treatment type)

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Follow-up up to 12 months (single application), SDF application frequency: single (one-time) application

Caries arrest rate (absolute proportion of lesions arrested) · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Follow-up >=12 months

Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth · 24 months, Biannual vs annual application

Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 12 mo

Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces… · 3-12 mo

Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 12 mo

Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 18 mo

Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces… · 3-12 mo

Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 30 mo

Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 12 mo