Same question across reviews · CL0194
intervention :: Laser/photodynamic -> White-spot/initial lesions
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
2
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CO2 laser combined with fluoride vs Fluoride alone Enamel demineralization / mineral loss · Human enamel specimens under cariogenic challenge (in situ / ex vivo) Clinical and ex-vivo effect of LASERs on prevention of early-enamel caries: systematic review & meta-analyses. (2024) | Narrative only (secondary question: laser-fluoride synergy). Takate: combined low-power CO2 laser plus 1.23% APF gave greater inhibition of mineral loss than either alone (APF after laser gave maximum inhibition).… | 2 studies | Ungraded |
Low-power CO2 laser irradiation (LLLT, 0.5 to 2 W) vs Placebo / no laser (control) Incidence of new white spot lesions (WSLs) · High caries-risk patients: fixed-orthodontic-appliance patients and children with partially erupted permanent molars · 3 to 18 months follow-up Clinical and ex-vivo effect of LASERs on prevention of early-enamel caries: systematic review & meta-analyses. (2024) | OR 0.21 [0.15, 0.30] | 3 studies · 182 participants | Ungraded |