Same question across reviews · CL0167

intervention :: Fluoride varnish -> Microbiological/plaque

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
3
current versions
GRADE rated
1
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care)
Adverse events and periodontal/secondary outcomes (gingival bleeding, gingival bleeding index, visible plaque index) · Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages… · Baseline and follow-up
Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth-… (2025)
Reported narratively by 3 trials (Arthur 2018, Sarti 2020, Jorge 2019). No adverse events were attributed to microinvasive treatment. Gingival bleeding index: no significant difference in Arthur 2018 and Jorge 2019 but…3 studiesUngraded
Oral health education/promotion (oral hygiene advice plus diet and feeding practice advice) combined with clinical treatment for mother's dentition (basic restorative and preventive; 1 trial included CHX varnish application) vs Standard care
Mother microbiological presence (high-level mutans streptococci / lactobacilli) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…
Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane
RR 0.53 [0.28, 1.03]1 study · 50 participantsUngraded
Chlorhexidine varnish (10%) vs Placebo or no treatment
Elevated mutans streptococci levels (>=4 with caries screen; high vs low) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with… · 6 to 36 months, permanent dentition
Chlorhexidine treatment for the prevention of dental caries in children and adolescents (2015) · Cochrane
RR 0.93 [0.80, 1.07]1 study · 496 participantsVery low

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