Same question across reviews · CL0157

intervention :: Fluoride toothpaste/dentifrice -> Periodontal/gingival

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
5
current versions
GRADE rated
4
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Toothpaste with a plaque-disclosing agent vs Conventional toothpaste
Gingival inflammation (short term) · Children aged 7 to 13 years with Down syndrome (mild to moderate ID); setting residential · Short term (<6 weeks)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
Toothpaste with a plaque-disclosing agent vs conventional toothpaste, children with Down syndrome. Ainamo & Bay Gingival Bleeding Index, mean 10 days; percent mean difference 18 (intervention) vs 8 (control), P<0.001…1 study · 40 participantsVery low
1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily
Gingival bleeding index (mean change from baseline) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 1.5 years
Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane
MD -0.07 [-0.15, 0.01]1 study · 97 participantsVery low
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Gingival bleeding at 6 to 7 months (Gingivitis Severity Index, proportion of sites bleeding, i.e. 2 or 3 on the Loe-Silness Gingival Index) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 7 months
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane
MD -0.13 [-0.17, -0.08]15 studies · 1998 participantsModerate
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Gingivitis at 6 to 9 months (Loe-Silness Gingival Index, 0 to 3 scale) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 9 months
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane
MD -0.27 [-0.33, -0.21]20 studies · 2743 participantsModerate
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Gingival bleeding at 6 months (number of sites bleeding on probing or spontaneously) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 months
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane
MD 0.14 [-1.11, 1.39]1 study · 329 participantsUngraded

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