Same question across reviews · CL0154

intervention :: Fluoride toothpaste/dentifrice -> Lesion arrest/remineralization

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
4
current versions
GRADE rated
4
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
10% CPP-ACP cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) vs Placebo cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice)
Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth) · 1 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.28 [0.97, 1.68]1 study · 45 participantsLow
10% CPP-ACP cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) vs Placebo cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice)
Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth) · 3 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.23 [1.06, 1.42]1 study · 45 participantsLow
5,000-ppm F (1.1% NaF) toothpaste or gel vs No treatment
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces… · 3-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 2.62 [1.49, 4.63]7 studies · 1304 participantsLow
10% CPP-ACP cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) vs Placebo cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice)
Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth) · 2 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.12 [0.93, 1.36]1 study · 45 participantsLow

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