Same question across reviews · CL0130

intervention :: Fluoride gel/foam -> Lesion arrest/remineralization

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
10
current versions
GRADE rated
10
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
1.23% APF gel vs 10% CPP-ACP paste
Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 2.19 [1.83, 2.61]3 studies · 4672 participantsModerate
1.23% APF gel vs No treatment
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 2.13 [1.79, 2.54]7 studies · 1575 participantsModerate
1.23% APF gel vs No treatment
Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 2.25 [2, 2.53]3 studies · 4672 participantsModerate
1.23% APF gel vs Sealant
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.08 [0.82, 1.41]7 studies · 1575 participantsLow
1.23% APF gel vs 5% NaF varnish
Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.05 [0.85, 1.29]3 studies · 4672 participantsLow
1.23% APF gel vs 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.08 [0.83, 1.4]7 studies · 1575 participantsLow
1.23% APF gel vs Resin infiltration + 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.67 [0.45, 0.99]7 studies · 1575 participantsLow
1.23% APF gel vs Sealant + 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.64 [0.44, 0.92]7 studies · 1575 participantsLow
1.23% APF gel + oral health education vs Oral health education
Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth) · 12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 2.47 [1.95, 3.13]1 study · 257 participantsModerate
1.23% APF gel vs 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Primary and permanent teeth with noncavitated occlusal carious lesions · 8 to 12 months
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2018)
RR 1.08 [0.83, 1.40]7 studiesLow

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