Same question across reviews · CL0122
intervention :: Exposure/condition: systemic-oral -> Microbiological/plaque
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
1
current versions
GRADE rated
1
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive) Salivary immunoglobulin A (SIgA) concentration · Children and adolescents (<18 years) living with HIV (CLWH) Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and… (2022) | Two studies gave divergent results: Subramaniam (2015) reported higher SIgA in children on ART for more than 3 years than pre-ART (8.6 (SD 2.9) vs 6.2 (SD 1.7) mg/dL; p < 0.001), whereas Pomarico (2009) found lower… | 2 studies | Very low |