Same question across reviews · CL0037

aetiology :: Exposure/condition: systemic-oral -> Microbiological/plaque

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
2
Questions
3
current versions
GRADE rated
0
Review overlap (CCA)
0.000
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Periodontitis vs No periodontitis
High salivary P. gingivalis (over 10^4 CFU/ml) · Adults · Overall
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 3.38 [1.46, 7.83]2 studiesUngraded
Periodontitis vs No periodontitis
High salivary S. mutans (over 10^4 CFU/ml) · Adults · Overall
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 0.82 [0.44, 1.51]2 studiesUngraded
Gastroesophageal or laryngopharyngeal reflux (GERD/LPR) vs Healthy individuals (controls)
Salivary function impairment (buffering capacity, flow rate, oral pH) · Adults with GERD/LPR reflux
Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020)
Mixed/controversial salivary findings: reduced salivary buffering capacity supported in three studies (Correa, Holbrook, Filipi) with low oral pH and reduced flow as additional factors in GERD patients, but Meurman and Schroeder found no significant salivary abnormalities; no pooled estimate.6 studiesUngraded

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