Same question across reviews · CL0029

aetiology :: Exposure: smoking/tobacco -> White-spot/initial lesions

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
1
current versions
GRADE rated
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Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
E-cigarette aerosol / e-liquid exposure (flavored and unflavored; nicotine and non-nicotine) vs Unexposed controls / unflavored e-liquid / conventional cigarette smoke
Enamel/dental hard-tissue changes and e-liquid cariogenic properties (demineralization, colour change, pH, sugar content, metals) · Oral bacteria (streptococci), dental hard tissue (enamel/dentin) and e-liquids studied in vitro/ex vivo (with a few…
The effects of electronic smoking on dental caries and proinflammatory markers: a systematic review and… (2025)
Narrative synthesis. In vitro studies showed e-liquids can be acidic (Fairchild 2021: 84% of vapes pH<5.5) and contain sugars (Fagan 2018 sucrose ~125 ug/ml; Kubica 2014 sucrose 0.76-72.93 ug/g), and e-cigarette…NRUngraded

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