Same question across reviews · CL0028

aetiology :: Exposure: smoking/tobacco -> Periodontal/gingival

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
3
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Self-reported gingivitis · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: a meta-analysis within Camoni et al. combining 6 primary studies found an association between e-cigarette use and self-reported gingivitis, with high heterogeneity (Camoni [28]); the umbrella…1 studyUngraded
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Oral microbiota composition (dysbiosis; increased periodontal/opportunistic pathogens) · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: reviews reported oral microbiota dysbiosis in e-cigarette users, including increased Porphyromonas gingivalis and Fusobacterium nucleatum and microbial shifts predisposing to oral infection…5 studiesUngraded
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Periodontitis / periodontal disease and periodontal parameters · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: e-cigarette use associated with increased risk of periodontal and gingival disease and worse periodontal parameters vs non-smokers (Tattar, Shabil, Figueredo, Yang [23,24,30,31]); no pooled…7 studiesUngraded

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