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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

3 questions in 1 reviews · cluster CL0028

current versions
No studies 0 · 0%Ungraded 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Self-reported gingivitis · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: a meta-analysis within Camoni et al. combining 6 primary studies found an association between e-cigarette use and self-reported gingivitis, with high heterogeneity (Camoni [28]); the umbrella…1 studyUngraded
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Oral microbiota composition (dysbiosis; increased periodontal/opportunistic pathogens) · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: reviews reported oral microbiota dysbiosis in e-cigarette users, including increased Porphyromonas gingivalis and Fusobacterium nucleatum and microbial shifts predisposing to oral infection…5 studiesUngraded
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Periodontitis / periodontal disease and periodontal parameters · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)
Narrative synthesis: e-cigarette use associated with increased risk of periodontal and gingival disease and worse periodontal parameters vs non-smokers (Tattar, Shabil, Figueredo, Yang [23,24,30,31]); no pooled…7 studiesUngraded