Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by RANK/RANKL/OPG Axis Expression and Response to Anti-RANKL Therapy in Gnathic Giant Cell Lesions: A Systematic Review and Meta-Analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Central Giant Cell Granuloma: A Decade of Institutional Experience and Curative Potential of Neoadjuvant Denosumab. Ying Ko et al. 2026 · Ko Chih Ying, Coleman Hedley, et al. · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research PMID:42301892 | 2026 | 1 | 1 | not extracted yet |
| Bone Remodeling Regulators in Central Giant Cell Granuloma: a Study of RANK and Osteocalcin Epression Taher et al. 2024 · TAHER Jawaher M, HAMDALA Zinah A., et al. · Medicina Moderna - Modern Medicine DOI:10.31689/rmm.2024.31.4.317 | 2024 | 1 | 1 | not extracted yet |
| Clinical and Radiologic Response of Central Giant Cell Granuloma to Denosumab: A 6-Year Prospective Observational Study. Rhou et al. 2022 · Rhou Yoon Ji Jina, Wang Che-Jen, et al. · Calcified tissue international PMID:35088118 | 2022 | 1 | 1 | not extracted yet |
| Denosumab for central giant cell granuloma in an Australian tertiary paediatric centre. Vanderniet et al. 2022 · Vanderniet Joel A, Wall Christie-Lee, et al. · Bone PMID:35331976 | 2022 | 1 | 1 | not extracted yet |
| RANKL inhibition for giant cell lesions of the jaw: A retrospective cohort analysis. Schreuder et al. 2022 · Schreuder Willem H, Lipplaa Astrid, et al. · European journal of cancer (Oxford, England : 1990) PMID:36174298 | 2022 | 1 | 1 | not extracted yet |
| Treatment of central giant cell granuloma in children with denosumab. Choe et al. 2021 · Choe Michelle, Smith Valeria, et al. · Pediatric blood & cancer PMID:33089644 | 2021 | 1 | 1 | not extracted yet |
| Efficacy and safety of denosumab treatment in a prepubertal patient with cherubism. Kawamura et al. 2020 · Kawamura Haruka, Watanabe Satoshi, et al. · Journal of pediatric endocrinology & metabolism : JPEM PMID:32649295 | 2020 | 1 | none stated | not extracted yet |
| Positive Outcomes of Denosumab Treatment in 2 Patients With Cherubism. Bar Droma et al. 2020 · Bar Droma Eitan, Beck-Rosen Guy, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:32649899 | 2020 | 1 | 1 | not extracted yet |
| Giant Cell Lesions of the Maxillofacial Skeleton Express RANKL by RNA In Situ Hybridization Regardless of Histologic Pattern. Stagner et al. 2019 · Stagner Anna M, Sajed Dipti P, et al. · The American journal of surgical pathology PMID:30998511 | 2019 | 1 | none stated | not extracted yet |
| Management of an aggressive giant cell granuloma of the mandible with denosumab: a case report. Hameed et al. 2019 · Hameed M, O'Connell J E, et al. · The British journal of oral & maxillofacial surgery PMID:31230854 | 2019 | 1 | none stated | not extracted yet |
| Peri-implant peripheral giant cell lesions: report of 13 new cases and comparative histological and immunohistochemical analysis with peripheral and… Morais et al. 2019 · Morais T-M, Soares C-D, et al. · Medicina oral, patologia oral y cirugia bucal PMID:31655833 | 2019 | 1 | none stated | not extracted yet |
| Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. Upfill-Brown et al. 2019 · Upfill-Brown Alexander, Bukata Susan, et al. · JBMR plus PMID:31687646 | 2019 | 1 | 1 | not extracted yet |
| Clinicopathological profile of central giant cell granulomas: An institutional experience and study of immunohistochemistry expression of p63 in… Hosur et al. 2018 · Hosur Mahadevi B, Puranik Rudrayya S, et al. · Journal of oral and maxillofacial pathology : JOMFP PMID:30158768 | 2018 | 1 | none stated | not extracted yet |
| Molecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation. Kadlub et al. 2018 · Kadlub Natacha, Sessiecq Quentin, et al. · Orphanet journal of rare diseases PMID:30236129 | 2018 | 1 | none stated | not extracted yet |
| Immunohistochemical expression of RANKL in oral giant cell lesions is predictive of aggressiveness. Martini et al. 2018 · Martini Georgia, Capella Diogo, et al. · Brazilian oral research PMID:30379236 | 2018 | 1 | none stated | not extracted yet |
| Immunohistochemical detection of the receptor activator of nuclear factor Kappa B ligand and c-fos in giant cell granuloma. Ahmed and Dunlap 2016 · Ahmed Atif A, Dunlap Charles · Journal of oral and maxillofacial pathology : JOMFP PMID:27194861 | 2016 | 1 | none stated | not extracted yet |
| Aggressive giant cell lesion of the jaws: a review of management options and report of a mandibular lesion treated with denosumab. O’Connell et al. 2015 · O'Connell John Edward, Bowe Conor, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:26340897 | 2015 | 1 | none stated | not extracted yet |
| Expression of proteases in giant cell lesions of the jaws, tendon sheath and salivary glands. Friedrich et al. 2010 · Friedrich Reinhard E, Eisenmann Julika, et al. · Anticancer research PMID:20592356 | 2010 | 1 | none stated | not extracted yet |
| Expression of receptor activator of NF-κB ligand and osteoprotegerin in peripheral giant cell granulomas of the jaws. Fanourakis et al. 2010 · Fanourakis Galinos, Lazaris Andreas C, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:20701665 | 2010 | 1 | none stated | not extracted yet |
| Immunohistochemical expression of RANK, GRalpha and CTR in central giant cell granuloma of the jaws. Sergio et al. 2005 · Tobón-Arroyave Sergio I, Franco-González Lina M, et al. · Oral oncology PMID:15878752 | 2005 | 1 | 1 | not extracted yet |
| Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. Li et al. 2003 · Liu Bo, Yu Shi-Feng, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:12787044 | 2003 | 1 | none stated | not extracted yet |