Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by BMP-2 in oral-maxillofacial bone augmentation: a systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Randomized, controlled clinical two-centre study using xenogeneic block grafts loaded with recombinant human bone morphogenetic protein-2 or… et al. (2018) · Thoma Daniel S, Payer Michael, et al. · Journal of clinical periodontology PMID:29150957 | 2018 | 2 | none stated | not extracted yet |
| Randomised controlled clinical trial of augmentation of the alveolar ridge using recombinant human bone morphogenetic protein 2 with hydroxyapatite… et al. (2017) · Nam J W, Khureltogtokh S, et al. · The British journal of oral & maxillofacial surgery PMID:28864147 | 2017 | 2 | none stated | not extracted yet |
| Efficacy of rhBMP-2/Hydroxyapatite on Sinus Floor Augmentation: A Multicenter, Randomized Controlled Clinical Trial. et al. (2015) · Kim H J, Chung J H, et al. · Journal of dental research PMID:26185033 | 2015 | 2 | none stated | not extracted yet |
| Buccal bone formation after flapless extraction: a randomized, controlled clinical trial comparing recombinant human bone morphogenetic protein… et al. (2014) · Coomes Angela M, Mealey Brian L, et al. · Journal of periodontology PMID:23826643 | 2014 | 2 | none stated | not extracted yet |
| Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical… et al. (2013) · de Freitas Rubens Moreno, Susin Cristiano, et al. · Journal of clinical periodontology PMID:23998375 | 2013 | 2 | none stated | not extracted yet |
| A randomized-controlled clinical trial evaluating clinical and radiological outcomes after 3 and 5 years of dental implants placed in bone… et al. (2009) · Jung Ronald E, Windisch Simone I, et al. · Clinical oral implants research PMID:19489935 | 2009 | 2 | none stated | not extracted yet |
| Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for… et al. (2009) · Triplett R Gilbert, Nevins Myron, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:19686934 | 2009 | 2 | none stated | not extracted yet |
| Randomized study evaluating recombinant human bone morphogenetic protein-2 for extraction socket augmentation. et al. (2005) · Fiorellini Joseph P, Howell T Howard, et al. · Journal of periodontology PMID:15857102 | 2005 | 2 | none stated | not extracted yet |
| De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation. et al. (2005) · Boyne Philip J, Lilly Leslie C, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:16297689 | 2005 | 2 | none stated | not extracted yet |
| The Clinical Efficacy and Safety of ErhBMP-2/BioCaP/β-TCP as a Novel Bone Substitute Using the Tooth-Extraction-Socket-Healing Model: A… Wei 2025 · Wei Lingfei, Sun Yuanyuan, et al. · Journal of clinical periodontology PMID:39478364 | 2025 | 1 | none stated | not extracted yet |
| Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 in Socket Preservation: A Randomized Controlled Clinical and Sequential Human… Reddy 2025 · Reddy Saravanan Sampoornam Pape, Francis Delfin Lovelina, et al. · Clinical and experimental dental research PMID:40388262 | 2025 | 1 | none stated | not extracted yet |
| Radiographic and histological evaluation of bone formation induced by rhBMP-2-incorporated biomimetic calcium phosphate material in clinical… Sun 2023 · Sun Yuanyuan, Xu Chunfeng, et al. · International journal of implant dentistry PMID:37843657 | 2023 | 1 | none stated | not extracted yet |
| Informative title: Guided bone regeneration with and without rhBMP-2: 17-year results of a randomized controlled clinical trial. Jung 2022 · Jung Ronald E, Kovacs Marionna N, et al. · Clinical oral implants research PMID:34958487 | 2022 | 1 | none stated | not extracted yet |
| Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP-2 and autogenous… Bienz 2021 · Bienz Stefan P, Payer Michael, et al. · Clinical oral implants research PMID:34543475 | 2021 | 1 | none stated | not extracted yet |
| Efficacy and safety of rhBMP/β-TCP in alveolar ridge preservation: a multicenter, randomized, open-label, comparative, investigator-blinded clinical… Han 2021 · Han Jeong Joon, Chang Ah Ryum, et al. · Maxillofacial plastic and reconstructive surgery PMID:34928477 | 2021 | 1 | none stated | not extracted yet |
| Randomized clinical study using xenograft blocks loaded with bone morphogenetic protein-2 or autogenous bone blocks for ridge augmentation - A… Thoma 2019 · Thoma Daniel S, Bienz Stefan P, et al. · Clinical oral implants research PMID:31172607 | 2019 | 1 | none stated | not extracted yet |
| Void space and long-term volumetric changes of maxillary sinus floor augmentation with comparison between hydroxyapatite soaked with bone… Yang 2019 · Yang Hoon Joo, Hwang Soon Jung · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery PMID:31395420 | 2019 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Recombinant Human Bone Morphogenetic Protein-2/Hydroxyapatite and Bovine Bone for New Bone Formation in Alveolar Ridge… Shim 2018 · Shim Jae-Yong, Lee Youngkyun, et al. · Implant dentistry PMID:30199421 | 2018 | 1 | none stated | not extracted yet |
| Histological analysis and gene expression profile following augmentation of the anterior maxilla using rhBMP-2/ACS versus autogenous bone graft. de Freitas 2016 · de Freitas Rubens Moreno, Susin Cristiano, et al. · Journal of clinical periodontology PMID:27440671 | 2016 | 1 | none stated | not extracted yet |
| Prospective randomized, controlled trial of sinus grafting using Escherichia-coli-produced rhBMP-2 with a biphasic calcium phosphate carrier… Kim MS 2015 · Kim Min-Soo, Lee Jung-Seok, et al. · Clinical oral implants research PMID:25186180 | 2015 | 1 | none stated | not extracted yet |
| The negative effect of combining rhBMP-2 and Bio-Oss on bone formation for maxillary sinus augmentation. Kao 2012 · Kao Daniel W K, Kubota Atsushi, et al. · The International journal of periodontics & restorative dentistry PMID:22254226 | 2012 | 1 | none stated | not extracted yet |
| Randomized clinical trial on the efficacy of Escherichia coli-derived rhBMP-2 with β-TCP/HA in extraction socket. Huh 2011 · Huh Jung-Bo, Lee Hyo-Jung, et al. · The journal of advanced prosthodontics PMID:22053248 | 2011 | 1 | none stated | not extracted yet |
| Effect of rhBMP-2 on guided bone regeneration in humans. Jung 2003 · Jung Ronald E, Glauser Roland, et al. · Clinical oral implants research PMID:12969359 | 2003 | 1 | none stated | not extracted yet |