Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Intranasal dexmedetomidine versus midazolam for pediatric dental sedation: a pooled analysis of clinical trials.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| A comparative evaluation of intranasal dexmedetomidine, midazolam and ketamine for their sedative and analgesic properties: a triple blind… Surendar 2014 · Surendar M Natarajan, Pandey R Kumar, et al. · The Journal of clinical pediatric dentistry PMID:25095322 | 2014 | 2 | none stated | not extracted yet |
| Sedative and behavioral effects of atomized intranasal midazolam in comparison with nebulized midazolam for children undergoing dental treatment: A… Elkhatib 2024 (1) · Elkhatib Amira Abdelhafeez, Mowafy Yousr Nader, et al. · International journal of paediatric dentistry PMID:39256918 | 2025 | 1 | none stated | not extracted yet |
| Evaluation of the Efficacy of Buccal Midazolam in Comparison With Intranasal Midazolam Sedation in Uncooperative Children During Dental Treatment. Arnaout 2025 · Arnaout Doaa, Altinawi Mohamed, et al. · International journal of dentistry PMID:40130021 | 2025 | 1 | none stated | not extracted yet |
| Comparative evaluation of the effectiveness and acceptance of intranasal dexmedetomidine and intranasal midazolam for sedation in children aged 5-8… Lalwani 2025 · Lalwani Yash, Dave Bhavna, et al. · Journal of dental anesthesia and pain medicine PMID:40201232 | 2025 | 1 | none stated | not extracted yet |
| Effect of Dexmedetomidine with or without Midazolam during procedural dental sedation in children: a randomized controlled clinical trial. ElKhatib 2024 (2) · ElKhatib Amira A, Ghoneim Tamer A M, et al. · BMC oral health PMID:39462365 | 2024 | 1 | none stated | not extracted yet |
| Comparison of sedative effects of intramuscular and intranasal midazolam for pediatric laceration repair in dental emergency department: A… Chang 2023 · Chang Huihui, Yuan Ye, et al. · Journal of stomatology, oral and maxillofacial surgery PMID:36707049 | 2023 | 1 | none stated | not extracted yet |
| Comparative evaluation of intranasal midazolam-ketamine, dexmedetomidine-ketamine, midazolam-fentanyl, and dexmedetomidine-fentanyl combinations for… Agarwal 2023 · Agarwal Abhilasha, Ansari Afroz Alam, et al. · Journal of dental anesthesia and pain medicine PMID:37034838 | 2023 | 1 | none stated | not extracted yet |
| Intranasal esketamine combined with oral midazolam provides adequate sedation for outpatient pediatric dental procedures: a prospective cohort study. Wang 2023 · Wang Jing, Zeng Jie, et al. · International journal of surgery (London, England) PMID:37288546 | 2023 | 1 | none stated | not extracted yet |
| Oral midazolam vs. intranasal dexmedetomidine plus oral midazolam for sedation of pediatric outpatients: a double-blinded randomized controlled trial. Nie 2023 · Nie Juan, Chen Chanchan, et al. · BMC anesthesiology PMID:37817075 | 2023 | 1 | none stated | not extracted yet |
| Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome… Hamod 2022 · Hamod Mohamad Nabil, Kouchaji Chaza, et al. · International journal of dentistry PMID:36160114 | 2022 | 1 | none stated | not extracted yet |
| Intranasal Dexmedetomidine Compared to a Combination of Intranasal Dexmedetomidine with Ketamine for Sedation of Children Requiring Dental… Sado-Filho 2021 · Sado-Filho Joji, Corrêa-Faria Patrícia, et al. · Journal of clinical medicine PMID:34199001 | 2021 | 1 | none stated | not extracted yet |
| Comparison between dexmedetomidine and esketamine in pediatric dentistry surgery. Xin 2021 · Xin Naixing, Xu Heng, et al. · Translational pediatrics PMID:35070829 | 2021 | 1 | none stated | not extracted yet |
| Randomized clinical trial on the efficacy of intranasal or oral ketamine-midazolam combinations compared to oral midazolam for outpatient pediatric… Sado-Filho 2019 · Sado-Filho Joji, Viana Karolline Alves, et al. · PloS one PMID:30856181 | 2019 | 1 | none stated | not extracted yet |
| A comparative assessment of intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients. Patel 2018 · Patel Vinod, Singh Neerja, et al. · Journal of the Indian Society of Pedodontics and Preventive Dentistry PMID:30324927 | 2018 | 1 | none stated | not extracted yet |
| Comparative evaluation of dexmedetomidine and midazolam-ketamine combination as sedative agents in pediatric dentistry: A double-blinded randomized… Malhotra 2016 · Malhotra Parul Uppal, Thakur Seema, et al. · Contemporary clinical dentistry PMID:27307665 | 2016 | 1 | none stated | not extracted yet |
| Intranasal Midazolam Sedation in a Pediatric Emergency Dental Clinic. Peerbhay 2016 · Peerbhay Fathima, Elsheikhomer Ahmed Mahgoub · Anesthesia progress PMID:27585415 | 2016 | 1 | none stated | not extracted yet |
| An evaluation of intranasal sufentanil and dexmedetomidine for pediatric dental sedation. Hitt 2014 · Hitt James M, Corcoran Toby, et al. · Pharmaceutics PMID:24662315 | 2014 | 1 | none stated | not extracted yet |