Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by The role of salivary lactoferrin as a potential biomarker for periodontal disease: a systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Oral Diagnostic Methods for the Detection of Periodontal Disease. Ramenzoni 2021 · Ramenzoni Liza L, Lehner Marc P, et al. · Diagnostics (Basel, Switzerland) PMID:33810094 | 2021 | 2 | 2 | not extracted yet |
| Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva. Ramenzoni 2021 · Ramenzoni Liza L, Hofer Deborah, et al. · BMC oral health PMID:34353321 | 2021 | 2 | none stated | not extracted yet |
| Effect of periodontal therapy on lactoferrin levels in gingival crevicular fluid. Yadav 2014 · Yadav N, Lamba A K, et al. · Australian dental journal PMID:24913177 | 2014 | 2 | none stated | not extracted yet |
| Elevated levels of salivary lactoferrin, a marker for chronic periodontitis? Glimvall 2012 · Glimvall P, Wickström C, et al. · Journal of periodontal research PMID:22471324 | 2012 | 2 | none stated | not extracted yet |
| Initial comparison of proteomic profiles of whole unstimulated saliva obtained from generalized aggressive periodontitis patients and healthy… Wu 2009 · Wu Y, Shu R, et al. · Journal of periodontal research PMID:19453860 | 2009 | 2 | none stated | not extracted yet |
| The investigation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin-1beta in gingival crevicular fluid: implications for… Wei 2004 · Wei Pi-Fen, Ho Kun-Yen, et al. · Journal of periodontal research PMID:15324348 | 2004 | 2 | none stated | not extracted yet |
| Gingival crevicular fluid lactoferrin levels in adult periodontitis patients. Tsai 1998 · Tsai C C, Kao C C, et al. · Australian dental journal PMID:9583225 | 1998 | 2 | none stated | not extracted yet |
| Determination of Salivary Lactoferrin Levels Before and After Non-Surgical Periodontal Treatment in Patients with Aggressive Periodontitis Ayettey-Adamafio 2025 · Ayettey- Adamafio Mary Naa Barkor, Tormeti Daniel, et al. · Postgraduate Medical Journal of Ghana DOI:10.60014/pmjg.v14i1.390 | 2025 | 1 | none stated | not extracted yet |
| Association between the concentration of salivary lactoferrin, smoking, and periodontal disease parameters: A randomized observational study Arab 2024 · Arab Hattan Mohamed, Abed Hassan, et al. · Saudi Journal of Oral Sciences DOI:10.4103/sjoralsci.sjoralsci_35_24 | 2024 | 1 | none stated | not extracted yet |
| Salivary Lactoferrin Levels, Disease Severity and Correlates in Patients with Chronic Periodontitis Presenting to a Tertiary Health Facility in… Orhue 2022 · ORHUE Vera Eigbibhalu, EHIZELE Adebola Oluyemisi, et al. · Nigerian Journal of Dental Research DOI:10.4314/njdr.v7i1.8 | 2022 | 1 | 1 | not extracted yet |
| Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva Ramenzoni 2021 (GCF, ref 56) · Ramenzoni Liza L., Hofer Deborah, et al. · BMC Oral Health DOI:10.1186/s12903-021-01743-5 | 2021 | 1 | 1 | not extracted yet |
| Salivary biomarker combination prediction model for the diagnosis of periodontitis in a Taiwanese population Wu 2018 · Wu Yun-Chun, Ning Lee, et al. · Journal of the Formosan Medical Association DOI:10.1016/j.jfma.2017.10.004 | 2018 | 1 | 1 | not extracted yet |
| The potential of salivary biomarkers for predicting the sensitivity and monitoring the response to nonsurgical periodontal therapy: A preliminary… Lee 2018 · Lee C.‐H., Chen Y.‐W., et al. · Journal of Periodontal Research DOI:10.1111/jre.12544 | 2018 | 1 | 1 | not extracted yet |
| Salivary biomarker combination prediction model for the diagnosis of periodontitis in a Taiwanese population. Wu 2018 · Wu Yun-Chun, Ning Lee, et al. · Journal of the Formosan Medical Association = Taiwan yi zhi PMID:29129647 | 2018 | 1 | none stated | not extracted yet |
| The potential of salivary biomarkers for predicting the sensitivity and monitoring the response to nonsurgical periodontal therapy: A preliminary… Lee 2018 · Lee C-H, Chen Y-W, et al. · Journal of periodontal research PMID:29882262 | 2018 | 1 | none stated | not extracted yet |
| Effect of periodontal therapy on lactoferrin levels in gingival crevicular fluid Yadav 2014 · Yadav N, Lamba AK, et al. · Australian Dental Journal DOI:10.1111/adj.12203 | 2014 | 1 | 1 | not extracted yet |
| Estimation of lactoferrin levels in gingival crevicular fluid before and after periodontal therapy in patients with chronic periodontitis. Kivadasannavar 2014 · Kivadasannavar Anasuya V, Pudakalakatti Pushpa S, et al. · Contemporary clinical dentistry PMID:24808691 | 2014 | 1 | none stated | not extracted yet |
| Can salivary activity predict periodontal breakdown in A. actinomycetemcomitans infected adolescents? Fine 2013 · Fine Daniel H., Furgang David, et al. · Archives of Oral Biology DOI:10.1016/j.archoralbio.2012.10.009 | 2013 | 1 | none stated | not extracted yet |
| Lactoferrin, A Marker for Periodontal Disease Lourenco 2013 · Lourenco Alan, Nakao Cristiano, et al. · Current HIV Research DOI:10.2174/1570162x11311030006 | 2013 | 1 | 1 | not extracted yet |
| Can salivary activity predict periodontal breakdown in A. actinomycetemcomitans infected adolescents? Fine 2013 · Fine Daniel H, Furgang David, et al. · Archives of oral biology PMID:23219180 | 2013 | 1 | none stated | not extracted yet |
| Lactoferrin, a marker for periodontal disease. Lourenco 2013 · Lourenço Alan G, Nakao Cristiano, et al. · Current HIV research PMID:23432422 | 2013 | 1 | none stated | not extracted yet |
| Elevated levels of salivary lactoferrin, a marker for chronic periodontitis? Glimvall 2012 · Glimvall P., Wickström C., et al. · Journal of Periodontal Research DOI:10.1111/j.1600-0765.2012.01479.x | 2012 | 1 | 1 | not extracted yet |
| Initial comparison of proteomic profiles of whole unstimulated saliva obtained from generalized aggressive periodontitis patients and healthy… Wu 2009 · Wu Y., Shu R., et al. · Journal of Periodontal Research DOI:10.1111/j.1600-0765.2008.01172.x | 2009 | 1 | 1 | not extracted yet |
| Lactoferrin and other markers from gingival crevicular fluid and saliva before and after periodontal treatment Jentsch 2004 · Jentsch H., Sievert Y., et al. · Journal of Clinical Periodontology DOI:10.1111/j.1600-051x.2004.00512.x | 2004 | 1 | none stated | not extracted yet |
| The investigation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin‐1β in gingival crevicular fluid: implications for… Wei 2004 · Wei Pi‐Fen, Ho Kun‐Yen, et al. · Journal of Periodontal Research DOI:10.1111/j.1600-0765.2004.00744.x | 2004 | 1 | none stated | not extracted yet |
| Lactoferrin and other markers from gingival crevicular fluid and saliva before and after periodontal treatment. Jentsch 2004 · Jentsch H, Sievert Y, et al. · Journal of clinical periodontology PMID:15191585 | 2004 | 1 | none stated | not extracted yet |
| Salivary lactoferrin and low‐<i>M</i><sub>r</sub> mucin MG2 in <i>Actinobacillus actinomycetemcomitans</i>‐associated periodontitis Groenink 1999 · Groenink J., Walgreen‐Weterings E., et al. · Journal of Clinical Periodontology DOI:10.1034/j.1600-051x.1999.260501.x | 1999 | 1 | 1 | not extracted yet |
| Salivary lactoferrin and low-Mr mucin MG2 in Actinobacillus actinomycetemcomitans-associated periodontitis. Groenink 1999 · Groenink J, Walgreen-Weterings E, et al. · Journal of clinical periodontology PMID:10355615 | 1999 | 1 | none stated | not extracted yet |
| Gingival crevicular fluid lactoferrin levels in adult per iodontitis patients Tsai 1998 · Tsai C‐C., Kao C. C., et al. · Australian Dental Journal DOI:10.1111/j.1834-7819.1998.tb00151.x | 1998 | 1 | 1 | not extracted yet |
| Peroxidases, Iactoferrin and lysozyme in peripheral blood neutrophils, gingival crevicular fluid and whole saliva of patients with localized… Suomalainen 1996 · Suomalainen K, Saxén L, et al. · Oral Diseases DOI:10.1111/j.1601-0825.1996.tb00213.x | 1996 | 1 | none stated | not extracted yet |
| Peroxidases, lactoferrin and lysozyme in peripheral blood neutrophils, gingival crevicular fluid and whole saliva of patients with localized… Suomalainen 1996 · Suomalainen K, Saxén L, et al. · Oral diseases PMID:8957925 | 1996 | 1 | none stated | not extracted yet |
| Lysozyme and Lactoferrin Quantitation in the Crevicular Fluid Friedman 1983 · Friedman Susan A., Mandel Irwin D., et al. · Journal of Periodontology DOI:10.1902/jop.1983.54.6.347 | 1983 | 1 | none stated | not extracted yet |
| Lysozyme and lactoferrin quantitation in the crevicular fluid. Friedman 1983 · Friedman S A, Mandel I D, et al. · Journal of periodontology PMID:6348246 | 1983 | 1 | none stated | not extracted yet |