Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles combined with injectable hydrogels in bone defect repair: a…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| PI3K/Akt pathway-mediated enhancement of bone and vascular regeneration by gelatin/hyaluronic acid/exosome composite scaffold in bone tissue… Wan 2025 · Wan Longbiao, Liu Feng, et al. · Biomaterials Advances DOI:10.1016/j.bioadv.2024.214064 | 2025 | 1 | none stated | not extracted yet |
| Engineered extracellular vesicles with sequential cell recruitment and osteogenic functions to effectively promote senescent bone repair Qi 2025 · Qi Lei, Wang Jing, et al. · Journal of Nanobiotechnology DOI:10.1186/s12951-025-03168-6 | 2025 | 1 | none stated | not extracted yet |
| Enhanced Tissue Regeneration Through Immunomodulatory Extracellular Vesicles Encapsulated in Diversified Silk‐Based Injectable Hydrogels Sun 2024 · Sun Liangyan, Xiao Menglin, et al. · Advanced Healthcare Materials DOI:10.1002/adhm.202401460 | 2024 | 1 | none stated | not extracted yet |
| Small Extracellular Vesicles Laden Oxygen-Releasing Thermosensitive Hydrogel for Enhanced Antibacterial Therapy against Anaerobe-Induced… Ming 2024 · Ming Leiguo, Qu Yanling, et al. · ACS Biomaterials Science & Engineering DOI:10.1021/acsbiomaterials.3c00493 | 2024 | 1 | none stated | not extracted yet |
| Osteoinductive Dental Pulp Stem Cell-Derived Extracellular Vesicle-Loaded Multifunctional Hydrogel for Bone Regeneration Wang 2024 · Wang Li, Wei Xinbo, et al. · ACS Nano DOI:10.1021/acsnano.3c11542 | 2024 | 1 | none stated | not extracted yet |
| Enhanced repair of osteoporotic bone defects through gelatin methylacryloyl loaded with exosomes Su 2024 · Su Shenghui, Wang Xiaoyong, et al. · AIP Advances DOI:10.1063/5.0220157 | 2024 | 1 | none stated | not extracted yet |
| Harnessing bone marrow mesenchymal stem cell-derived extracellular vesicles and biomimetic peptide WKYMVm in self-healing hydrogel for enhanced bone… Luo 2024 · Luo Keyu, Jin Yufei, et al. · Journal of Tissue Engineering DOI:10.1177/20417314241306681 | 2024 | 1 | none stated | not extracted yet |
| Versatile Hypoxic Extracellular Vesicles Laden in an Injectable and Bioactive Hydrogel for Accelerated Bone Regeneration Deng 2023 · Deng Jiajia, Wang Xin, et al. · Advanced Functional Materials DOI:10.1002/adfm.202211664 | 2023 | 1 | none stated | not extracted yet |
| Multifunctional Injectable Hydrogel Microparticles Loaded with miR‐29a Abundant BMSCs Derived Exosomes Enhanced Bone Regeneration by Regulating… Pan 2023 · Pan Shaowei, Yin Zhaowei, et al. · Small DOI:10.1002/smll.202306721 | 2023 | 1 | none stated | not extracted yet |
| Injectable MMP1-sensitive microspheres with spatiotemporally controlled exosome release promote neovascularized bone healing Yang 2023 · Yang Yang, Zheng Weihan, et al. · Acta Biomaterialia DOI:10.1016/j.actbio.2022.11.065 | 2023 | 1 | none stated | not extracted yet |
| Programmed release of vascular endothelial growth factor and exosome from injectable chitosan nanofibrous microsphere-based PLGA-PEG-PLGA hydrogel… Han 2023 · Han Shuang, Yang Hongye, et al. · International Journal of Biological Macromolecules DOI:10.1016/j.ijbiomac.2023.126721 | 2023 | 1 | none stated | not extracted yet |
| Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration Lu 2023 · Lu Wei, Zeng Min, et al. · Materials Today Bio DOI:10.1016/j.mtbio.2023.100569 | 2023 | 1 | none stated | not extracted yet |
| Integrated Osteoinductive Factors─Exosome@MicroRNA-26a Hydrogel Enhances Bone Regeneration Kuang 2023 · Kuang Haizhu, Ma Jing, et al. · ACS Applied Materials & Interfaces DOI:10.1021/acsami.2c21933 | 2023 | 1 | none stated | not extracted yet |
| Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular… Guo 2023 · Guo Rongkang, Wu Chaohan, et al. · Journal of Nanobiotechnology DOI:10.1186/s12951-023-02201-w | 2023 | 1 | none stated | not extracted yet |
| PF127 Hydrogel-Based Delivery of Exosomal CTNNB1 from Mesenchymal Stem Cells Induces Osteogenic Differentiation during the Repair of Alveolar Bone… He 2023 · He Longlong, Zhou Qin, et al. · Nanomaterials (Basel, Switzerland) PMID:36985977 | 2023 | 1 | none stated | not extracted yet |
| Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIF Li 2022 · Li Rui, Li Dize, et al. · Stem Cell Research & Therapy DOI:10.1186/s13287-022-02823-1 | 2022 | 1 | none stated | not extracted yet |
| Umbilical Mesenchymal Stem Cell-Derived Exosome-Encapsulated Hydrogels Accelerate Bone Repair by Enhancing Angiogenesis Zhang 2021 · Zhang Yuntong, Xie Yang, et al. · ACS Applied Materials & Interfaces DOI:10.1021/acsami.0c22671 | 2021 | 1 | none stated | not extracted yet |
| Integration of Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes with Hydroxyapatite-Embedded Hyaluronic Acid-Alginate Hydrogel for Bone… Yang 2020 · Yang Shuo, Zhu Biao, et al. · ACS Biomaterials Science & Engineering DOI:10.1021/acsbiomaterials.9b01363 | 2020 | 1 | none stated | not extracted yet |
| Generation of Small RNA-Modulated Exosome Mimetics for Bone Regeneration Fan 2020 · Fan Jiabing, Lee Chung-Sung, et al. · ACS Nano DOI:10.1021/acsnano.0c05122 | 2020 | 1 | none stated | not extracted yet |