Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Investigating the applicability of polar fabric phase sorptive extraction for the HPLC quantitation of salivary vitamin B12 following administration… Korpeti 2023 · Korpeti Anastasia, Manousi Natalia, et al. · Talanta PMID:36989615 | 2023 | 1 | none stated | not extracted yet |
| Parenteral vs Oral Vitamin B12 in Children With Nutritional Macrocytic Anemia: A Randomized Controlled Trial. Tandon 2022 · Tandon Rahul, Thacker Jigar, et al. · Indian pediatrics PMID:35642923 | 2022 | 1 | none stated | not extracted yet |
| Vitamin B12 supplementation orally and intramuscularly in people with obesity undergoing gastric bypass. Ramos 2021 · Ramos Rafael Jacques, Mottin Cláudio Corá, et al. · Obesity research & clinical practice PMID:33622624 | 2021 | 1 | none stated | not extracted yet |
| Sublingual methylcobalamin treatment is as effective as intramuscular and peroral cyanocobalamin in children age 0-3 years. Orhan Kilic 2021 · Orhan Kiliç Betül, Kiliç Serhat, et al. · Hematology (Amsterdam, Netherlands) PMID:34871525 | 2021 | 1 | none stated | not extracted yet |
| Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomised, non-inferiority… Sanz-Cuesta 2020 · Sanz-Cuesta Teresa, Escortell-Mayor Esperanza, et al. · BMJ open PMID:32819927 | 2020 | 1 | none stated | not extracted yet |
| Comparison of Sublingual and Intramuscular Administration of Vitamin B12 for the Treatment of Vitamin B12 Deficiency in Children. Tugba-Kartal 2020 · Tuğba-Kartal Ayşe, Çağla-Mutlu Zeynep · Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion PMID:33053572 | 2020 | 1 | none stated | not extracted yet |
| Various Neurological Symptoms with Vitamin B12 Deficiency and Posttreatment Evaluation. Arican 2020 · Arıcan Pinar, Bozkurt Oznur, et al. · Journal of pediatric neurosciences PMID:33936299 | 2020 | 1 | none stated | not extracted yet |
| Comparison of sublingual vs. intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency. Bensky 2019 · Bensky Merav Jacobson, Ayalon-Dangur Irit, et al. · Drug delivery and translational research PMID:30632091 | 2019 | 1 | none stated | not extracted yet |
| Comparison of the efficacy of parenteral and oral treatment for nutritional vitamin B12 deficiency in children. Sezer 2018 · Sezer Rabia Gönül, Akoğlu Handan Ayhan, et al. · Hematology (Amsterdam, Netherlands) PMID:29577819 | 2018 | 1 | none stated | not extracted yet |
| Efficacy of oral compared with intramuscular vitamin B-12 supplementation after Roux-en-Y gastric bypass: a randomized controlled trial. Schijns 2018 · Schijns Wendy, Homan Jens, et al. · The American journal of clinical nutrition PMID:29931179 | 2018 | 1 | none stated | not extracted yet |
| Early biomarker response and patient preferences to oral and intramuscular vitamin B12 substitution in primary care: a randomised parallel-group… Metaxas 2017 · Metaxas Corina, Mathis Deborah, et al. · Swiss medical weekly PMID:28421567 | 2017 | 1 | none stated | not extracted yet |
| Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomised trial. Parry-Strong 2016 · Parry-Strong Amber, Langdana Fali, et al. · The New Zealand medical journal PMID:27355231 | 2016 | 1 | none stated | not extracted yet |
| Effect of administration route on the pharmacokinetics of cobalamin in elderly patients: a randomized controlled trial. Tillemans 2014 · Tillemans Monique P H, Donders Eline M V J, et al. · Current therapeutic research, clinical and experimental PMID:25031664 | 2014 | 1 | none stated | not extracted yet |
| Sa1100 Randomized Open Label Trial Comparing Efficacy of Oral Versus Intramuscular Vitamin B12 Supplementation for Treatment of Vitamin B12 Deficiency Saraswathy 2012 · Saraswathy Arun Ramaswamy, Dutta Amit, et al. · Gastroenterology DOI:10.1016/s0016-5085(12)60808-7 | 2012 | 1 | none stated | not extracted yet |
| Oral vitamin B12 replacement: an effective treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients. Kim 2011 · Kim Hyoung-Il, Hyung Woo Jin, et al. · Annals of surgical oncology PMID:21556950 | 2011 | 1 | none stated | not extracted yet |
| Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low… Castelli 2011 · Castelli M Cristina, Friedman Kristen, et al. · Clinical therapeutics PMID:21600388 | 2011 | 1 | none stated | not extracted yet |
| A single-center, double-blinded, randomized controlled study to evaluate the relative efficacy of sublingual and oral vitamin B-complex… Yazaki 2006 · Yazaki Yuka, Chow Gigi, et al. · Journal of alternative and complementary medicine (New York, N.Y.) PMID:17109579 | 2006 | 1 | none stated | not extracted yet |
| Oral vitamin B12 therapy in vitamin B12 deficiency. Roth 2004 · Roth Mark, Orija Israel · The American journal of medicine PMID:14984828 | 2004 | 1 | none stated | not extracted yet |
| Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route. Sharabi 2003 · Sharabi Amir, Cohen Eytan, et al. · British journal of clinical pharmacology PMID:14616423 | 2003 | 1 | none stated | not extracted yet |
| Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Bolaman 2003 · Bolaman Zahit, Kadikoylu Gurhan, et al. · Clinical therapeutics PMID:14749150 | 2003 | 1 | none stated | not extracted yet |
| Enteral vitamin B12 supplements reverse postgastrectomy B12 deficiency. Adachi 2000 · Adachi S, Kawamoto T, et al. · Annals of surgery PMID:10903597 | 2000 | 1 | none stated | not extracted yet |
| Vitamin B12 absorption test and oral treatment in 14 children with selective vitamin B12 malabsorption. Altay 1999 · Altay C, Cetin M · Pediatric hematology and oncology PMID:10100276 | 1999 | 1 | none stated | not extracted yet |
| Effective treatment of cobalamin deficiency with oral cobalamin. Kuzminski 1998 · Kuzminski A M, Del Giacco E J, et al. · Blood PMID:9694707 | 1998 | 1 | none stated | not extracted yet |
| Clinical efficacy of intravenous plus oral mecobalamin in patients with peripheral neuropathy using vibration perception thresholds as an indicator… Yamane 1995 · Yamane K., Usui T., et al. · Current Therapeutic Research DOI:10.1016/0011-393x(95)85135-6 | 1995 | 1 | none stated | not extracted yet |
| Adachi 2000 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Altay 1999 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Arican 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Bensky 2019 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Bolaman 2003 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Castelli 2011 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Korpeti 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Kuzminski 1998 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Metaxas 2017 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Orhan Kilic 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Parry-Strong 2016 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Ramos 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Roth 2004 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Sanz-Cuesta 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Saraswathy 2012 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Schijns 2018 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Sezer 2018 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Sharabi 2003 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Tanaka 1981 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Tandon 2022 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Tillemans 2012 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Tugba-Kartal 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Yamane 1995 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Yazaki 2006 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |