Primary study · included by 1 review

Pain Perception During Minimally Invasive Caries Removal in Children: A Randomized Clinical Trial Comparing Chemo-Mechanical Caries Removal.

Goel 2025 · Goel Dhirja, Awasthi Neha, Singh Yanina, et al. · Journal of International Society of Preventive & Community Dentistry · 2025

Included by

Outcome this study informsPooled effectEvidenceCertainty
Pain (binary: no pain or comfort)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
OR 3.35 [1.01, 11.17]5 studies · 260 participantsHigh
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -0.04 [-0.26, 0.17]NRGRADE not reported
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -2.22 [-2.88, -1.55]NRGRADE not reported
Pain, no pain (comfort) rate
Any chemomechanical caries removal gel (BRIX3000, Carisolv, Carie Care, Papacarie/Papacarie DUO) vs Conventional mechanical caries removal (rotary bur, curette/spoon excavator or polymer bur)
OR 2.85 [1.61, 5.04]5 studies · 260 participantsHigh
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -1.7 [-2.19, -1.21]9 studies · 1635 participantsHigh
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -0.52 [-0.81, -0.24]NRGRADE not reported

1 including review in total.