Primary study · included by 1 review

Outcomes, Predictors of Retreatment, and Complications After Repeat Gamma Knife Radiosurgery for Trigeminal Neuralgia: A Single-Center Retrospective Cohort Study.

Seha 2025 · Seha Biljana, Bogosavljevic Vojislav, Grujicic Danica, et al. · Cureus · 2025

Included by

Repeat gamma knife radiosurgery for recurrent trigeminal neuralgia: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Seha 2025 · Table 1; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Dysgeusia after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 11.31 [3.68, 21.74]	2 studies · 53 participants	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0022	8 studies	GRADE not reported
Facial hypoesthesia after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 39.04 [26.65, 51.42]	12 studies · 564 participants	GRADE not reported
BNI pain score I-III (favorable pain outcome) after latest treatment Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After latest (repeat) treatment	Proportion (%) 76.68 [69.70, 82.46]	13 studies · 606 participants	GRADE not reported
Corneal dryness after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 10.99 [3.42, 21.54]	3 studies · 199 participants	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 68.44 [58.44, 78.44]	12 studies · 1078 participants	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0086	6 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0047	8 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0012	6 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0011	10 studies	GRADE not reported

1 including review in total.