Primary study · included by 1 review

Silver Diamine Fluoride vs Atraumatic Restoration for Managing Dental Caries in Schools: A Cluster Randomized Clinical Trial.

Ruff 2025 · Ruff Ryan Richard, Gawande Aditi Ashish, Xu Qianhui, et al. · JAMA network open · 2025

Included by

Silver diamine fluoride versus atraumatic restorative treatment for management of childhood caries: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Ruff 2025 · Table 1; Ref 20; Fig. 2

Outcome this study informs	Pooled effect	Evidence	Certainty
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months	RR 1.46 [0.98, 2.20]	4 studies · 1149 participants	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.25 [0.97, 1.59]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.30 [0.65, 2.59]	3 studies · 767 participants	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.26 [1.03, 1.54]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.06 [0.95, 1.17]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.23 [0.94, 1.62]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.12 [0.96, 1.31]	4 studies · 11129 participants	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.21 [1.02, 1.44]	7 studies · 11896 participants	Very low
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.15 [0.96, 1.38]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · More than 12 months	RR 0.98 [0.83, 1.16]	3 studies · 10747 participants	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.27 [1.04, 1.54]	6 studies	GRADE not reported
Caries arrest Silver diamine fluoride (SDF), any concentration or frequency vs Atraumatic restorative treatment (ART) with glass ionomer cement · 12 months or longer follow-up	RR 1.29 [1.07, 1.55]	6 studies	GRADE not reported

1 including review in total.