Primary study · included by 1 review

Comparative evaluation of BRIX3000 and Carisolv in chemomechanical caries removal in immature permanent first molars: a randomized controlled trial.

Rajab 2025 · Rajab Mohammad Malek, Karkoutly Mawia, Alsalameh Samar, et al. · BMC oral health · 2025

Included by

Comparative efficacy of chemomechanical caries removal and conventional mechanical caries removal for the treatment of primary molar caries in children: a meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Rajab 2025 · Table 1; reference list; forest plots Figs. 3 to 9
Outcome this study informsPooled effectEvidenceCertainty
Caries removal efficacy
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD 1.18 [0.5, 1.85]4 studies · 287 participantsHigh
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -0.04 [-0.26, 0.17]NRGRADE not reported
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -2.22 [-2.88, -1.55]NRGRADE not reported
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -1.7 [-2.19, -1.21]9 studies · 1635 participantsHigh
Pain intensity (continuous)
Chemomechanical caries removal (CMCR), any agent vs Conventional mechanical caries removal (bur, curette or polymer bur)
SMD -0.52 [-0.81, -0.24]NRGRADE not reported

1 including review in total.