Primary study · included by 1 review

Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study.

Kolay 2025 · Kolay Duygu, Kırıcı Damla · BMC oral health · 2025

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Kolay 2025 · Reference 19; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.05 [0.9, 1.23]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.02 [0.94, 1.11]	9 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.05 [0.93, 1.18]	10 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.03 [0.98, 1.08]	12 studies · 989 participants	Moderate
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.07 [0.93, 1.23]	2 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.04 [0.95, 1.13]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.01 [0.88, 1.16]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.03 [0.93, 1.15]	6 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.04 [0.97, 1.12]	6 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.02 [0.98, 1.06]	10 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 0.99 [0.9, 1.09]	7 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	RR 1.03 [0.96, 1.11]	9 studies	GRADE not reported

1 including review in total.